Drug discovery
Drug discovery

Drug discovery

Dr YU Yuanyuan
Assistant Professor, Teaching and Research Division

Dr. Yuanyuan Yu is currently an Assistant Professor in the School of Chinese Medicine. She obtained her PhD in biochemistry from Faculty of Medicine, the University of Hong Kong in 2015. After graduation, she joined School of Chinese Medicine, Hong Kong Baptist University to undertake the postdoctoral training from 2015 to 2019.

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Her current research interests include 1) optimization of the aptamer selection methodologies; 2) Aptamer-based translational medicine and drug discovery; 3) aptamer structural biology.

Li F, Lu J, Liu J, Liang C, Wang M, Wang L, Li D, Yao H, Zhang Q, Wen J, Zhang ZK, Li J, Lv Q, He X, Guo B, Guan D, Yu Y, Dang L, Wu X, Li Y, Chen G, Jiang F, Sun S, Zhang BT, Lu A, Zhang G. (2017) A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cancer. Nat Commun 8(1):1390

Zhuo Z†, Yu Y†, Wang M, Li J, Zhang Z, Liu J, Wu X, Lu A, Zhang G & Zhang BT. (2017) Recent advances in SELEX technology and aptamer applications in biomedicine. Int J Mol Sci 18(10). (co-first author)

Wu X†, Shaikh AB†, Yu Y†, Li Y, Ni S, Lu A & Zhang G. (2017) Potential diagnostic and therapeutic applications of oligonucleotide aptamers in breast cancer. Int J Mol Sci 18(9). (co-first author)

Zhang Q, Lv H, Wang L, Chen M, Li F, Liang C, Yu Y, Jiang F, Lu A, Zhang G. (2016) Recent Methods for Purification and Structure Determination of Oligonucleotides. Int J Mol Sci 17(12).

Lv Q†, Meng Z†, Yu Y†, Jiang F, Guan D, Liang C, Zhou J, Lu A & Zhang G. (2016) Molecular Mechanisms and Translational Therapies for Human Epidermal Receptor 2 Positive Breast Cancer. Int J Mol Sci 17(12). (co-first author)