Systems medicine
- Assistant Dean (Student Learning Experience);
- Professor
Biography 
Dr Jade Shi received her bachelor's degree in physics at Zhongshan University in 1999. She went on to pursue her Ph.D. study in biophysics at the University of Michigan, Ann Arbor and was awarded the degree in 2006. She then conducted her postdoctoral work in Tim Mitchison's lab in the Department of Systems Biology at Harvard Medical School. She is now a professor in the Department of Physics and Assistant Dean (Student Learning Experience) in Hong Kong Baptist University and also the Director of the Center for Quantitative Systems Biology.
+ More InformationResearch Interests
- Dynamics of anticancer drug response using novel 3D cancer organoid and spheroid models;
- Cytototoxic dynamics of Natural killer cells against distinct cancer targets;
- Development of new immuno-oncology drug and drug target through profiling immunomodulating traditional Chinese medicine.
Google Scholar (Feb 1, 2023)
- Citations: 2,604
- h-index: 24
- i10-index: 29
Selected Publications
Y Zhu, J Xie, J Shi, Rac1/ROCK-driven membrane dynamics promote natural killer cell cytotoxicity via granzyme-induced necroptosis, BMC biology 19 (1), 1-14 (2021).
Single-cell transitional dynamics unravel stimulus-and cell type-dependent signaling outputs of distinct p53 regulatory feedback motifs, J Xie, L Zhang, Y Zhu, X Liang, J Shi, bioRxiv (2021).
Magnetic iron oxide nanoparticle-hollow mesoporous silica Spheres: Fabrication and potential application in drug delivery, Y Teng, Y Du, J Shi, PWT Pong, Current Applied Physics 20 (2), 320-325 (2020).
Rac1/ROCK-driven membrane dynamics promote Natural Killer cell cytotoxicity via necroptosis
Y Zhu, J Xie, J Shi, bioRxiv, 867127 (2020).
Sensitive and Specific Colorimetric Detection of Cancer Cells Based on Folate-Conjugated Gold–Iron-Oxide Composite Nanoparticles, Y Teng, J Shi, PWT Pong, ACS Applied Nano Materials 2 (11), 7421-7431 (2019).